ABSTRACT
To compare mean platelet volume in patients with psoriasis and healthy individuals. This case control study was conducted in outpatients department and indoor of department of Dermatology, DHQ Hospital, Faisalabad. The duration of study was six months. Thirty consecutive patients of psoriais, 20 to 60 years of age and thirty age and gender matched healthy individuals were selected. 2cc venous blood sample from each subject was sent to the pathology laboratory of DHQ Hospital. Mean platelet volume [MPV] was measured as a part of blood complete analysis in Medonic M series Haematology analser. MPV was found higher in the patients of psoriasis as compared to the healthy individuals. The mean value of MPV in the case group was 8.24 +/- 1.22 fl, whereas in the control group, it was 7.29 +/- 0.77 fl [p<0.05]. The study demonstrated that mean platelet volume is increased in patients with psoriasis as compared to healthy individuals. Such patients are at an increased risk of cardiovascular complications
Subject(s)
Humans , Male , Female , Platelet Activation , Blood Platelets , Arthritis, Psoriatic/blood , Cardiovascular DiseasesABSTRACT
The objective of this study was to compare the effect of supra scapular nerve block and intra articular injection to relieve pain and reduce disability in the patients of frozen shoulder. It was a quasi experimental study. The study was conducted at the department of Orthopedics, Pakistan Railway Hospital, Rawalpindi, fromAugust 2011 toSeptember 2012. Patients diagnosed as the cases of frozen shoulder in outpatient department of Orthopedics irrespective of their gender were included in the study. Forty patients and 50 shoulders were divided into two groups by randomization, one group received single suprascapular nerve block and second group received single intra-articular steroid injection. Both groups were advised for physiotherapy after injection. Patients' pain levels and ranges of movement were assessed over a period of twelve weeks. The study included 40 patients and 50 shoulders to a single suprascapular nerve block and intra articular steroid injection. The mean age of the patients was 49.4 + 9.97 and the range was 40-60 years. There were 16 females and 24 male patients. Post injection assessment of patients was done at two, six, eight and twelve weeks. There was a significant decrease in pain and marked improvement in range of movement with supra scapular nerve block than with intra articular injection. Patients' pain levels and ranges of movement were assessed over a twelve week period. Suprascapular nerve block produced a faster and more complete resolution of pain and restoration of range of movement than intra articular injection
ABSTRACT
A 45 years old male patient was diagnosed as a case of motor neuron disease. Within four years he became paralyzed and bed ridden. Due to severe respiratory tract infection, the patient developed respiratory failure and was put on ventilator. Later on the infection was successfully treated but the patient could not be weaned from the ventilator because of the paralysis of respiratory muscles. It was obvious that the patient would require life long ventilatory support so the same was arranged at the patient's home and he was discharged from the hospital after nine months. Now, for the past six years the patient is on ventilatory support
ABSTRACT
The objective of this study was to observe the success rate, difficulties and complications during the technique of spinal anesthesia through para median approach in elderly frail patients with spinal abnormalities, for femur fracture surgery. Case series study was performed at Pakistan Naval Shifa Hospital, Karachi, Pakistan from August 2002 to July 2003, after approval from Scientific Research Council of the Hospital and consent of the patients. Forty elderly patients with spinal abnormalities, ASA II, age 88 +/- 8 years, weight 68.5 +/- 3.5 kg, declared high-risk for anesthesia, scheduled for femur fracture surgery under spinal anesthesia, were selected for study after failure of lumbar puncture [LP] through midline approach at L3-4 or L4-5 level. First routine LP was performed, if failed, then second LP through para median approach was attempted. The success rate of the para median approach was 100%. In 4 patients [10%] there was bloody tap and LP was done after selecting another space or re-adjusting the needle in the same space. Forty% patients felt paraesthesia during the advancement of spinal needle into the sub-arachnoid space. In conclusion, in the elderly frail patients with spinal deformity, declared high-risk for general anesthesia and where lumbar puncture through midline approach fails due to spinal abnormalities, para median route is an alternate safe approach with success rate of 100%